Over nearly two decades, Dennis Rader murdered at least 10 people in the Wichita, Kansas area under the pseudonym BTK ('Bind, Torture, Kill'). But despite his repeated taunts to the police and media, investigators were unable to hone in on a suspect.

Manson's murder conviction in 1971 left many, including his biological family, with guilt and unanswered questions.

The disappearance of LaToyia Figueroa, who was Black and Hispanic, sparked controversy in 2005 when the case didn't garner the media attention it deserved.

In the 1960s, an unidentified serial killer terrorized London sex workers. The Hammersmith Nude Murders remains one of Britain's most infamous unsolved crimes.

Posthumous DNA testing proved what Roger Keith Coleman repeatedly denied—that the Virginia man raped and murdered his sister-in-law in 1981.

After the Golden State Killer's arrest in 2018, dozens of rape victims learned their assaults weren't isolated incidents but the work of a serial killer. Read how many survivors bonded through mutual trauma.

Shayna Hubers shot and killed her boyfriend, Ryan Poston, claiming it was self-defense. But at the murder scene, there were few indications of a domestic disturbance. Read more about this bizarre case.

Peter Sutcliffe had the makings of a serial killer before he claimed his first victim and continued on a murderous spree that terrorized England for nearly five years.

An episode of 'Killer Cases' focuses on a mysterious triple murder in Pensacola that brought whispers of black magic to the Florida panhandle. 

Florida mom Casey Anthony lied to investigators about the 2008 disappearance of her 2-year-old daughter Caylee Anthony for weeks. We've compiled a list of some of her most questionable statements.