A&E True Crime looks at five pairs of infamous best friends who did everything together—including murder.

Since his incarceration in 2004, for the murders of 71 teenage girls and women, 'Green River Killer' Gary Ridgway has lived a life of isolation at Washington State Penitentiary.

Margaret Press, co-founder of DNA Doe Project, spoke with A&E True Crime about how investigative genetic genealogy helped identify Francis Wayne Alexander as Victim No. 5 of serial killer John Wayne Gacy.

The 1995 murder of Maurizio Gucci, former heir to the Gucci fashion empire, led to the conviction of his ex-wife Patrizia Reggiani, and others, in a high-profile case that made headlines across the world.

On July 29, 1994, 7-year-old Megan Kanka was killed by Jesse Timmendequas, a convicted sex offender who lived across the street.

From teen victims Libby German and Abby Williams to Alonzo Brooks to the 'Jennings 8' and more, we look at some murder cases that investigators could use the public's help in solving.

On January 13, 1992, the serial killer changed his plea from not guilty to guilty but insane, which removed the need for a criminal trial and forced the verdict to be based on the jury's decision of his mental state.

Robert A. Jensen, former co-owner of a mass fatality response company, speaks with A&E True Crime about the impact of reuniting families with the material accessories of a life cut short.

The Florida man stole from his family and then murdered his parents and brother after they disapproved of his "relationship" with a Bulgarian cam model he had never met in real life

The officer's murder was investigated by the FBI for more than five decades. And while all of the prime suspects were members of the Ku Klux Klan, no one has ever been charged.